The study was published in Nature Microbiology
Cudurka faafa ee coronavirus, cilmi baarayaashu wali waxay baarayaan dhacdadii dhabta ahayd ee ay ku dhacday isugeynta coronavirus-ka cusub ee xayawaanka iyo bini-aadamka. Koox saynisyahano ah ayaa laga yaabaa inay ogaadeen jawaabta su’aasha dad badan ay weydiinayeen bilo, sida lagu sheegay daraasad lagu daabacay Nature Microbiology.
Kooxda saynisyahannada ee ka socda Mareykanka, Shiinaha, iyo Yurub waxay isbarbar dhigeen qaababka isku-beddelka SARS-CoV-2, fayraska sababa COVID-19, iyo fayrasyada kale, waxayna abuureen taariikh horumarineed ee fayrasyada la xiriira. Waxay ogaadeen abtirsiinta masuulka ka ah soo saarista fayraska abuuray cudurka COVID-19 ee faafa ayaa ku jiray fiidmeerta, sida lagu sheegay daraasadda.
Seynisyahanno ayaa ogaaday abtirsiinta mas’uulka ka ah soo saarista fayraska abuuray cudurka COVID-19 ee faafa ayaa ku jiray fiidmeerta, sida lagu sheegay daraasadda. (iStock)
“Isku soo wada duuboo falanqeynteenu waxay tilmaameysaa in fiidmeerta ay yihiin keydka ugu muhiimsan ee qowmiyada SARS-CoV-2. In kasta oo ay suurtagal tahay in baangiyo, ama nooc kale oo aan illaa hadda la ogaan, ay u dhaqmi kareen sidii marti-geliye dhexdhexaad ah oo fududeynaya gudbinta aadanaha, caddaynta hadda jirta waxay la jaanqaadaysaa fayraska oo ku soo kordhay fiidmeerta taasoo keentay fiidmeerta fiitamiinada oo ku celcelin kara qaybta sare ee neef mareenka labadaba aadanaha iyo baangiga, “qorayaasha daraasadda ayaa ku yiri warbixinta la daabacay.
Kooxda cusub ee loo yaqaan ‘coronavirus’ ayaa ka soo baxday fayrasyada kale ee fiidmeerta ah 40-70 sano ka hor, kooxda cilmi-baarayaasha ayaa sidaas yidhi.
Abtirsiinta dhalaysa ee ‘SARS-CoV-2’ waxay ku dhex wareegeysay fiidmeerta fiidmeeryo muddo tobanaan sano ah,” ayay qorayaashu qoreen.
Warbixin ay siiyeen Fox News, cilmi-baarayaashu waxay ku sheegeen in SARS-CoV-2 ay hiddo ahaan la mid tahay (qiyaastii 96%) tan loo yaqaan ‘RaTG13 coronavirus’ oo laga helay muunad ka mid ah fiidmeerta Rhinolophus affinis fardohoe ee 2013 ee gobolka Yunnan, Shiinaha, laakiin laga weeciyay RaTG13 sanadkii 1969.
“Awoodda lagu qiyaasi karo waqtiyada kala duwanaanshaha ka dib kala-soocida taariikhda dib-u-ururinta, taas oo ah wax aan ku soo saarnay wadashaqeyntan, waxay u horseedi kartaa aragti ku saabsan asalka cuduro fara badan oo kala duwan,” Philippe Lemey, oo ka tirsan Waaxda Evolutionary and Computational Virology, KE Leuven, ayaa lagu yiri sii deynta.
The coronavirus-ka cusub wuxuu sifooyin la wadaagayaa xubnaha waayeelka ah ee ku abtirsada ee la xiriira qaybta soo-dhaweynta (RBD) ee borotiinka kor u kaca ah, taas oo u oggolaanaysa inay ku xirnaato unugyada soo-dhoweynta bini-aadamka, ayay qorayaashu sheegeen.
“Mawduuceeda qabashada-ku-xirnaanta, oo muhiim u ah gaar ahaanta soo-dhoweeyeyaasha ACE2, waxay umuuqataa inay tahay aabe awoowe oo lala wadaago fayrasyada fiidmeerta oo aan ahayn mid dhowaan lagu helay dib-u-cusboonaysiin,” sida lagu sheegay daraasadda.
“Tani waxay ka dhigan tahay in fayrasyo kale oo awood u leh inay dadka qaadaan ay ku dhex wareegayaan fiidmeerta fardo ee Shiinaha,” wada-wadaha daraasadda, David Robertson, oo ah borofisar ku takhasusay cilmiga kombiyuutarka ee MRC-Jaamacadda Glasgow Center for Virus Research, ayaa sharraxay sii deynta.
Qorayaasha daraasaddan ayaa sheegay in kooxaha kale ee cilmi-baarayaashu ay ku qaldanaayeen soo-jeedinta in isbeddelada isbeddelka ee ka dhacay baangiyada ay u oggolaatay sheeko-faneedka cusub ee loo yaqaan ‘coronavirus’ in loo gudbiyo aadanaha. Robertson wuxuu yiri, “SARS-CoV-2’s RBD isku xigxiga ilaa iyo hada waxaa kaliya laga helay fayrasyo yar oo pangolin ah.
KORONAVIRUS WUXU KA CAAWIN KARAA BADARAAYAASHA LA dagaalanka kansarka, sida uu qabo cilmi-baaraha
“Inkasta oo ay suurtagal tahay in pangolins laga yaabo inay u dhaqmeen sidii marti-geliye dhexdhexaad ah oo fududeynaya gudbinta SARS-CoV-2 dadka, haddana ma jiraan wax caddeyn ah oo muujinaya in cudurka pangolin uu yahay mid looga baahan yahay fayrasyada fiidmeerta inay u gudbaan aadanaha,” ayuu Robertson sidoo kale ku sheegay Halkii, cilmi-baaristeena waxay soo jeedinaysaa in SARS-CoV-2 ay u badan tahay inay kobcisay awoodda lagu soo saari karo qaybta sare ee neef mareenka dadka iyo baangiga. ”
Hirgelinta nidaamyo lagula soconayo cudurada aadanaha waqtiga dhabta ah iyo tijaabinta fiidmeerta wanaagsan ayaa loo baahan yahay si loo ogaado noolaha cusub ee faafa ugana hortago aafooyinka mustaqbalka, qorayaashu waxay ku sheegeen sii deynta.
“Furaha kormeerka guuleysta,” ayuu yiri Robertson, “waa ogaanshaha fayrasyada la raadinayo iyo kala-mudnaanta kuwa sida fudud u faafin kara aadanaha. Waxay ahayd inaan sifiican ugu diyaar garawno virus labaad oo SARS ah. ”