10″ Sep”2022″ AP
Saynis yahanadu waxay ogaadeen sida wasakhowga hawadu u keeno kansarka sanbabada
Daraasad cusub ayaa muujinaysa khatarta caafimaad ee ay keeni karaan walxaha yaryar ee ay soo saaraan shiidaalka fosilka.
Saynis yahanadu waxa ay sheegeen in ay ogaadeen habka ay wasakhowga hawadu u kiciso kansarka sanbabada ee dadka aan sigaarka cabbin, daahfurka mid ka mid ah khubarada ayaa ku amaanay “tallaabo muhiim u ah sayniska – iyo bulshada”.
Cilmi-baadhistu waxay muujisay khatarta caafimaad ee ay leeyihiin walxaha yaryar ee ay soo saaraan shiidaalka fosil, taasoo dhalisay baaqyo degdeg ah oo degdeg ah oo lagula dagaallamayo isbeddelka cimilada.
Waxa kale oo ay waddada u xaari kartaa beer cusub oo ka hortagga kansarka, sida uu qabo Charles Swanton oo ka tirsan Machadka Francis Crick ee Boqortooyada Ingiriiska.
Swanton wuxuu soo bandhigay cilmi-baarista, oo aan weli lagu daabicin joornaal dib-u-eegis ah, oo ka tirsan Ururka Midowga Yurub ee Caafimaadka Oncology ee shir-sannadeedka ee Paris Sabtidii.
Wasakhowga hawada ayaa muddo dheer loo maleynayay inay la xiriirto khatarta sare ee kansarka sanbabada ee dadka aan waligood sigaar cabbin
“Laakiin runtii ma garanayno in wasakhdu ay si toos ah u keento kansarka sanbabada – ama sida,” Swanton ayaa u sheegay wakaaladda wararka ee AFP.
Dhaqan ahaan waxaa loo malaynayay in soo-gaadhista kansarka, sida kuwa qiiqa sigaarka ama wasakhowga, ay keento isbeddellada DNA-da oo markaa noqda kansar.
Cilmi-baaris hore ayaa muujisay in isbeddellada DNA-da ay jiri karaan iyaga oo aan keenin kansar – iyo in inta badan kansarka deegaanku aysan keenin isbeddellada.
Kiniinka kansarka mustaqbalka
Kooxda cilmi-baarista ee Machadka Francis Crick iyo University College London waxay falanqeeyeen xogta caafimaadka in ka badan 460,000 oo qof oo ku nool England, South Korea iyo Taiwan.
Waxay ogaadeen in soo-gaadhista qaybo yaryar oo wasakhaysan PM2.5 – oo ka yar 2.5 micrometers (microns) guud ahaan – ay keentay khatarta sii kordheysa ee isku-beddelka hidda-wadaha koritaanka epidermal (EGFR).
Daraasadaha shaybaarka ee jiirarka, kooxdu waxay muujisay in qaybo ka mid ah ay keeneen isbeddel ku yimid hidda-wadaha EGFR iyo sidoo kale fayraska Kirsten rat sarcoma (KRAS), kuwaas oo labadaba lala xiriiriyay kansarka sanbabada.
Ugu dambeyntii, waxay falanqeeyeen ku dhawaad 250 muunado oo unugyada sambabada bini’aadamka ah oo aan waligood la kulmin kansarka sigaarka ama wasakhowga culus
Inkasta oo sambabku caafimaad qabaan, waxay heleen isbeddellada DNA-da boqolkiiba 18 ee hiddo-wadaha EGFR iyo 33 boqolkiiba hiddo-wadaha KRAS.
Kaliya halkaas ayay fadhiyaan, ”ayuu yidhi Swanton, isaga oo intaa ku daray in isbeddelladani ay u muuqdaan kuwo sii kordhaya da’da.
“Kaligood, malaha kuma filna inay wadaan kansarka,” ayuu yidhi.
Laakiin marka unuggu soo gaadho wasakhowga, waxay kicin kartaa “jawaab bogsiin boog ah” oo sababa caabuq, ayuu yiri Swanton.
Oo haddii unuggaasi “uu keeno isbeddel, wuxuu markaas samayn doonaa kansar”, ayuu raaciyay.
“Waxaan bixinay hab bayooloji ah oo ka dambeeya wixii markii hore ahaa hal-xidhaale,” ayuu yidhi.
Tijaabo kale oo lagu sameeyay jiirarka, cilmi-baarayaashu waxay muujiyeen in antibody-ku uu xannibi karo dhexdhexaadiyaha – oo loo yaqaan interleukin 1 beta – kaas oo kicinaya caabuqa, ka joojinaya kansarka inuu bilaabo markii hore.
Swanton waxa uu sheegay in uu rajaynayo in natiijadu “ay keento sababo miro dhal ah oo mustaqbalka ah waxa noqon kara ka hortagga kansarka molecular, halkaas oo aanu dadka ku siin karno kaniini, laga yaabee maalin kasta, si loo yareeyo khatarta kansarka”
Suzette Delaloge, oo madax ka ah barnaamijka ka hortagga kansarka ee machadka Gustave Roussy ee Faransiiska, ayaa sheegtay in cilmi-baaristu ay ahayd “mid kacaan ah, sababtoo ah ficil ahaan ma aanan haysan wax ka hor ah oo muujinaya habkan beddelka ah ee samaynta kansarka”.
“Daraasaddu waa tallaabo muhiim u ah sayniska – iyo bulshada sidoo kale, waxaan rajeynayaa,” ayay u sheegtay AFP.
“Tani waxay furaysaa albaab weyn, labadaba aqoonta, laakiin sidoo kale siyaabo cusub oo looga hortago” kansarka si uu u kobco, ayuu yidhi Delaloge, oo aan ku lug lahayn cilmi-baarista laakiin ka hadlay shirkii Sabtidii.
“Bannaanbax heerkan ah waa inuu ku qasbaa mas’uuliyiinta inay u dhaqmaan si heer caalami ah.”
Tony Mok, oo ku takhasusay kansarka kana tirsan jaamacadda Shiinaha ee Hong Kong, ayaa cilmi-baadhistan ugu yeedhay “mid xiiso leh”.
Cilmi-baadhisyo kale ayaa PM2.5 ku xidhay 250,000 dhimasho sannadkii oo ka dhasha kansarka sanbabada oo keliya.
<壯陽藥 !– /wp:paragraph –>“Aniga iyo adiga waxaan leennahay doorasho ku saabsan inaan sigaar cabno iyo in kale, laakiin ma hayno doorasho ku saabsan hawada aan neefsaneyno,” ayuu yiri Swanton, oo sidoo kale ah dhakhtarka madaxa ee Cancer Research UK, oo ahaa maalgeliyaha ugu weyn ee cilmi-baarista. .
“Marka la eego in laga yaabo in shan jeer in ka badan dadka ay la kulmaan heerarka wasakhda xun ee tubaakada, waxaad arki kartaa in tani ay tahay dhibaato weyn oo caalami ah,” ayuu raaciyay.
“Waxaan wax ka qaban karnaa oo keliya haddii aan aqoonsanno xiriirka dhabta ah ee ka dhexeeya caafimaadka cimilada iyo caafimaadka aadanaha
